Ovarian cancer occurs when cells in the ovaries start to grow uncontrollably. Unfortunately, this type of cancer often remains hidden until it spreads to the abdomen, making treatment quite difficult. This is why preventive strategies and regular screenings are crucial in minimizing the serious complications associated with ovarian cancer. Recent findings suggest that ovarian cancer is not solely an ovarian-origin disease; it can also begin in the fallopian tubes, underscoring the complexity of its pathogenesis and the need for comprehensive screening approaches to identify it earlier in its course[1].
While there's no guaranteed method to prevent ovarian cancer, there are certainly ways to decrease the likelihood of developing it. Some risk factors, like aging and family history, are beyond our control, but there are others we can manage. Notably, research indicates that the use of oral contraceptives can significantly impact risk, providing a potential strategy for women, especially those with a family history of breast or ovarian cancer.
What Can I Do To Reduce the Risk of Developing Ovarian Cancer?
Here are several strategies that might help lower the risk of ovarian cancer:
1) Oral Contraceptives
Using oral contraceptives, or birth control pills, has been linked to a reduced risk of ovarian cancer. Women who have taken these pills for five years or longer may have about a 50% lower risk compared to those who haven't[2]. This protective effect appears to extend even to women with a familial predisposition to ovarian cancer, suggesting that oral contraceptives could serve as an important chemopreventive measure[3]. However, it's worth noting that these contraceptives come with potential side effects, so it's important for women to discuss the risks with their healthcare providers.
2) Hysterectomy and Tubal Ligation
Surgical procedures like hysterectomy (removal of the uterus) and tubal ligation (tying off the fallopian tubes) can decrease the risk of ovarian cancer. However, health experts recommend these surgeries only for legitimate medical reasons and not merely as a preventive measure against ovarian cancer. It's essential to weigh the benefits against potential complications and long-term implications of such surgeries.
3) Giving Birth
Having one or more children, especially if the first child is born before the age of 25, may help reduce the risk of ovarian cancer. Parity has been associated with a lower risk, possibly due to hormonal changes during pregnancy that may influence ovarian function.
4) Breastfeeding
Women who breastfeed for a year or more tend to have a lower risk of developing ovarian cancer. This may be attributed to the hormonal alterations associated with lactation, which can impact ovarian activity and reduce the overall number of ovulatory cycles throughout a woman's reproductive life.
5) Nutritious Diet and Exercise
As per the American Cancer Society, a healthy diet combined with regular physical activity can modestly lower the risk of ovarian cancer. Research supports the idea that a balanced diet rich in fruits, vegetables, and whole grains, along with maintaining a healthy weight, can contribute to overall cancer risk reduction[4].
While these strategies may help in reducing the risk of ovarian cancer, it's important to remember that there's no foolproof way to prevent it entirely. Moreover, these approaches may not be suitable for everyone as they come with their own risks and benefits. If you're looking to discuss your options and find ways to lower your risk of ovarian cancer, consider reaching out to a specialist online.
References:
- Vera Loizzi, Marco Cerbone, Francesca Arezzo, Erica Silvestris, Gianluca Raffaello Damiani, Gerardo Cazzato, Ettore Cicinelli, Gennaro Cormio. Contraception as chemoprevention of ovarian cancer in BRCA1 and BRCA2 women.. PubMed. 2024.
- Aminah Jatoi, Nathan R Foster, Kimberly R Kalli, Robert A Vierkant, Zhiying Zhang, Melissa C Larson, Brooke Fridley, Ellen L Goode. Prior oral contraceptive use in ovarian cancer patients: assessing associations with overall and progression-free survival.. PubMed. 2015.
- J S Ferris, M B Daly, S S Buys, J M Genkinger, Y Liao, M B Terry. Oral contraceptive and reproductive risk factors for ovarian cancer within sisters in the breast cancer family registry.. PubMed. 2014.
- Kristine Crane. Oral contraceptives as ovarian cancer prevention.. PubMed. 2011.
- Eduardo L Franco, Eliane Duarte-Franco. Ovarian cancer and oral contraceptives.. PubMed. 2008.