Cancer is widely recognized as the second leading cause of death globally. It can be a daunting subject, and many people avoid discussing it. But raising awareness about cancer is crucial, and engaging in physical activity is a key aspect of this. Not only does exercise keep you fit, but it also plays a significant role in lowering cancer risks. Research indicates that higher levels of physical activity can be associated with a reduction in cancer risk by about 10% to 25% for up to 13 different types of cancer, with strong evidence particularly for colon and breast cancer[1]. Let's explore how being active can help reduce your likelihood of developing cancer.
How Exercise Impacts Cancer Risk:
Physical activity has a variety of biological effects on the body. Here are some ways exercise can influence specific cancer risks:
- Exercise can lower levels of sex hormones like estrogen and growth factors, which are known to contribute to cancer development and progression[2].
- It helps prevent elevated insulin levels in the blood, which have been linked to increased cancer risk, particularly in hormonally driven malignancies[5].
- Regular physical activity reduces inflammation in the body, a known contributor to cancer progression[3].
- It enhances your immune system's functionality, which is crucial for identifying and eliminating cancer cells[4].
- Exercise alters bile acid metabolism, thereby reducing gastrointestinal exposure to potential carcinogens[4].
- It shortens the time food spends traveling through the digestive tract, minimizing carcinogen exposure[4].
- Being active helps to prevent obesity, which is a known risk factor for several types of cancer, with obesity linked to increased incidence and mortality in cancers such as prostate and breast cancer[2].
Particularly, exercise can be crucial in lowering the risk for cancers such as breast, colon, endometrial, and lung cancers.
Recommended Exercises for Cancer Risk Reduction:
The American College of Sports Medicine suggests aiming for at least 150 minutes of moderate exercise or 75 minutes of vigorous activity each week. Ideally, a mix of both is best. You can break your activity into short sessions of about 10 minutes each. Moderate exercises might include walking or yoga, while vigorous activities could be running, fast cycling, or swimming.
Additionally, try to avoid long periods of sitting. Staying sedentary can lead to obesity, a significant cancer risk factor[2]. Aim to move every hour — even just for a couple of minutes. And don't forget about your kids! Encouraging them to stay active will help them form healthy habits for life.
References:
- Edward Giovannucci. An Integrative Approach for Deciphering the Causal Associations of Physical Activity and Cancer Risk: The Role of Adiposity.. PubMed. 2018.
- Maria M Rubinstein, Kristy A Brown, Neil M Iyengar. Targeting obesity-related dysfunction in hormonally driven cancers.. PubMed. 2021.
- Wendy Demark-Wahnefried, Jeffery W Nix, Gary R Hunter, Soroush Rais-Bahrami, Renee A Desmond, Balu Chacko, Casey D Morrow, Maria Azrad, Andrew D Frugé, Yuko Tsuruta, Travis Ptacek, Scott A Tully, Roanne Segal, William E Grizzle. Feasibility outcomes of a presurgical randomized controlled trial exploring the impact of caloric restriction and increased physical activity versus a wait-list control on tumor characteristics and circulating biomarkers in men electing prostatectomy for prostate cancer.. PubMed. 2016.
- Alessandro Ottaiano, Chiara De Divitiis, Monica Capozzi, Antonio Avallone, Carmen Pisano, Sandro Pignata, Salvatore Tafuto. Obesity and Cancer: Biological Links and Treatment Implications.. PubMed. 2018.
- Ali R Nasiri, Marcos R Rodrigues, Zongyu Li, Brooks P Leitner, Rachel J Perry. SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia.. PubMed. 2019.