New COVID Variant – What Is It?
As expected, the novel Coronavirus (SARS-CoV-2) has undergone many mutations since it first emerged a year back. The current variant, known as VUI-202012/01 (the first “Variant Under Investigation” in December 2020) or lineage B.1.1.7, has been linked to a rapid increase in COVID-19 cases in some parts of the UK, raising concerns among scientists. This variant has been identified with multiple mutations in the spike protein, which are believed to significantly enhance the virus's transmissibility, making it approximately 70% more contagious than previous strains. Research indicates that such mutations may affect not only the virus's ability to spread but also its interaction with the host's immune response, further complicating the management of the pandemic [2].
We are left wondering if these changes lead to different symptoms, considering how much remains unknown about this new strain. Fortunately, current evidence suggests that this variant has not been associated with more severe symptoms compared to prior variants [1].
Why Is the New Variant More Contagious?
The mutations in the coronavirus spike proteins, which cover the virus's outer surface and give it that spiny appearance, are believed to enhance its contagiousness. These changes may enhance the virus's binding affinity to the ACE2 receptor, which facilitates entry into human cells, thus promoting higher viral loads in infected individuals [3]. At this stage, it's hard to say for certain, and more studies need to be conducted to fully understand the transmissibility of this new strain.
What Are the Symptoms to Look Out For?
So far, the symptoms associated with the new variant have been similar to those of the initial strain, but doctors are closely monitoring the situation. Once infected with the new strain, symptoms can appear anywhere from 2 to 14 days later, and they may range from mild to severe. Common symptoms include:
- Fever.
- Cough.
- Shortness of breath.
- Fatigue or tiredness.
- Muscle pain.
- Headache.
- Loss of taste or smell.
- Sore throat.
- Runny nose.
- Nausea or vomiting.
- Diarrhea.
In addition to these symptoms, the Centre for Disease Control and Prevention (CDC) has highlighted the following alarming signs for COVID-19:
- Breathing difficulty.
- Continuous chest pain.
- Confusion.
- Inability to stay awake.
- Bluish discoloration of lips.
These symptoms can indicate severe pneumonia and low oxygen levels in the blood, so they should not be taken lightly. Immediate medical attention is crucial, especially as COVID-19-related complications such as Guillain-Barré Syndrome have been observed in some patients [5].
How to Keep Your Family Safe?
The most effective way to halt the spread of this new variant and any future variants is by:
- Wearing a mask.
- Washing your hands with soap and water for at least 20 seconds.
- Staying six feet away from anyone who is not part of your household.
- Avoiding crowds.
- Steering clear of poorly ventilated areas.
Currently, there is no evidence suggesting that the COVID-19 vaccines will be ineffective against the new variant. However, until scientists confirm this, it's wise to follow preventive measures even if you have already been vaccinated [4].
If you have questions or concerns regarding COVID-19 symptoms or prevention, consider utilizing our online doctor consultation service. You can easily talk to a doctor online, or even consult with an AI doctor if you prefer. Our chat doctor is available to help guide you through these challenging times.
References:
- Omid Dadras, Alimohamad Asghari, Atefe Nosratzahi. Persistent Hiccups as an Atypical Initial Presentation of COVID-19: A Case Report.. PubMed. 2022.
- Vincent Lucansky, Marek Samec, Tatiana Burjanivova, Eva Lukacova, Zuzana Kolkova, Veronika Holubekova, Eva Turyova, Andrea Hornakova, Tibor Zaborsky, Petar Podlesniy, Lenka Reizigova, Zuzana Dankova, Elena Novakova, Renata Pecova, Andrea Calkovska, Erika Halasova. Comparison of the methods for isolation and detection of SARS-CoV-2 RNA in municipal wastewater.. PubMed. 2023.
- Anastasia Williams, Heather Branscome, Pooja Khatkar, Gifty A Mensah, Sarah Al Sharif, Daniel O Pinto, Catherine DeMarino, Fatah Kashanchi. A comprehensive review of COVID-19 biology, diagnostics, therapeutics, and disease impacting the central nervous system.. PubMed. 2021.
- Antonella Zizza, Virginia Recchia, Alessandra Aloisi, Marcello Guido. Clinical features of COVID-19 and SARS epidemics. A literature review.. PubMed. 2021.
- Jitendra Singh, Nilesh Kumar, Anju Dinkar. Demographic, Clinical, and Investigational Characteristics of COVID-19- related Guillain-Barré Syndrome with Differences from Typical and Another Virus-related Guillain-Barré Syndrome.. PubMed. 2022.